'Revolutionary' new hip replacement procedure

'Revolutionary' new hip replacement procedure

'Revolutionary' new hip replacement procedure

First published in Southampton Daily Echo: Photograph of the Author by , Reporter

IT is a risky operation that can take months to recover from.

But researchers in Southampton say they have discovered a “revolutionary”

method that could prevent many from having to undergo painful hip replacements.

Surgeons based at hospitals in the city have developed a stem cell treatment that could treat the common bone disease, osteonecrosis.

The illness can cause significant bone damage in the hip, when poor blood supply causes bone tissue to die.

At the moment, the main treatment for the condition is a total hip replacement – but city scientists say their new procedure could dispense with the need for that operation.

The method has been developed by Doug Dunlop, a consultant orthopaedic surgeon at Southampton General Hospital, and Professor Richard Oreffo, a specialist in musculoskeletal science at the University of Southampton.

The treatment involves extracting stem cells from the bone marrow of the patient and mixing it with other cleaned, crushed bone.

Dead and damaged tissue is then removed from the hip joint by surgeons, and the resulting hole is filled with the bone marrow mixture.

Mr Dunlop says initial test results are encouraging.

He said: “Although this work is still ongoing, several patients who have had the procedure have reacted very well and, if we get the results we are hoping for, these patients won’t need to have their hip joints replaced – they should be fixed completely.”

Professor Oreffo added: “By using stem cells to send out chemical signals to blood vessels, we hope the body will continue to create new vessels in the hip which supply enough nutrients to maintain bone strength.”

Mr Dunlop will be joined by other medical experts at the University Hospital Southampton NHS Trust’s orthopaedic open evening on Thursday, at the Lyndhurst Park Hotel in Lyndhurst.

Anyone interested in attending the event, which takes place between 7pm and 9pm, should call 023 8079 4853 or email uhsmember@uhs.nhs.

uk.

Comments (15)

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12:17pm Mon 28 May 12

wossit says...

Hip Hip Hooray
Hip Hip Hooray wossit
  • Score: 0

1:17pm Mon 28 May 12

Dan Soton says...

Great, maybe now SHA can drop the Fluoridation of Southampton's drinking water and put all the saved money into stem cell therapy to regrow teeth or parts of teeth
Great, maybe now SHA can drop the Fluoridation of Southampton's drinking water and put all the saved money into stem cell therapy to regrow teeth or parts of teeth Dan Soton
  • Score: 0

3:37pm Mon 28 May 12

Barney123 says...

Good to see they are doing research into Hip Replacements, but shame they can't get the basics right. When my Mum went into the General to get her hip replaced they managed to break her pelvis at the same time!
Good to see they are doing research into Hip Replacements, but shame they can't get the basics right. When my Mum went into the General to get her hip replaced they managed to break her pelvis at the same time! Barney123
  • Score: 0

3:46pm Mon 28 May 12

bobbyboy says...

does it work on the knees and can i give it a go save the iron work for later.
does it work on the knees and can i give it a go save the iron work for later. bobbyboy
  • Score: 0

7:08pm Mon 28 May 12

memush says...

Great to see good news being given space in the echo (for a change) well done and continued success.
Great to see good news being given space in the echo (for a change) well done and continued success. memush
  • Score: 0

1:20am Tue 29 May 12

Dan Soton says...

Dan Soton wrote:
Great, maybe now SHA can drop the Fluoridation of Southampton's drinking water and put all the saved money into stem cell therapy to regrow teeth or parts of teeth
interesting coincidence.

-

Princess Anne opens new £54m Scottish stem cell research centre.

By NATALIE WALKER.
Published on Monday 28 May 2012 12:24.

The University of Edinburgh- run centre will carry out cutting-edge stem cell research to help find therapies for patients with conditions such as multiple sclerosis, Parkinson’s disease, motor neurone disease and heart and liver diseases.

The centre is the first large-scale, purpose-built facility of its kind and provides accommodation for up to 250 stem cell scientists.

http://tinyurl.com/b
qelsku
[quote][p][bold]Dan Soton[/bold] wrote: Great, maybe now SHA can drop the Fluoridation of Southampton's drinking water and put all the saved money into stem cell therapy to regrow teeth or parts of teeth[/p][/quote]interesting coincidence. - Princess Anne opens new £54m Scottish stem cell research centre. By NATALIE WALKER. Published on Monday 28 May 2012 12:24. The University of Edinburgh- run centre will carry out cutting-edge stem cell research to help find therapies for patients with conditions such as multiple sclerosis, Parkinson’s disease, motor neurone disease and heart and liver diseases. The centre is the first large-scale, purpose-built facility of its kind and provides accommodation for up to 250 stem cell scientists. http://tinyurl.com/b qelsku Dan Soton
  • Score: 0

1:28am Tue 29 May 12

Dan Soton says...

Dan Soton wrote:
Dan Soton wrote:
Great, maybe now SHA can drop the Fluoridation of Southampton's drinking water and put all the saved money into stem cell therapy to regrow teeth or parts of teeth
interesting coincidence.

-

Princess Anne opens new £54m Scottish stem cell research centre.

By NATALIE WALKER.
Published on Monday 28 May 2012 12:24.

The University of Edinburgh- run centre will carry out cutting-edge stem cell research to help find therapies for patients with conditions such as multiple sclerosis, Parkinson’s disease, motor neurone disease and heart and liver diseases.

The centre is the first large-scale, purpose-built facility of its kind and provides accommodation for up to 250 stem cell scientists.

http://tinyurl.com/b

qelsku
another interesting coincidence.
-


Cloning teeth for implantation using stem cells.

Wednesday, May 02, 2012.

The teeth can be grown in the lab and implanted in the patient or they could actually grow inside the patient's mouth, filling in empty spaces with new teeth in just a few months.

-

Dr. Murray says growing replacement teeth from stem cells will pave the way for growing other complete replacement body parts. He says teeth are relatively safe because if a tooth fails, it can simply be extracted.

http://tinyurl.com/c
u7bxec
[quote][p][bold]Dan Soton[/bold] wrote: [quote][p][bold]Dan Soton[/bold] wrote: Great, maybe now SHA can drop the Fluoridation of Southampton's drinking water and put all the saved money into stem cell therapy to regrow teeth or parts of teeth[/p][/quote]interesting coincidence. - Princess Anne opens new £54m Scottish stem cell research centre. By NATALIE WALKER. Published on Monday 28 May 2012 12:24. The University of Edinburgh- run centre will carry out cutting-edge stem cell research to help find therapies for patients with conditions such as multiple sclerosis, Parkinson’s disease, motor neurone disease and heart and liver diseases. The centre is the first large-scale, purpose-built facility of its kind and provides accommodation for up to 250 stem cell scientists. http://tinyurl.com/b qelsku[/p][/quote]another interesting coincidence. - Cloning teeth for implantation using stem cells. Wednesday, May 02, 2012. The teeth can be grown in the lab and implanted in the patient or they could actually grow inside the patient's mouth, filling in empty spaces with new teeth in just a few months. - Dr. Murray says growing replacement teeth from stem cells will pave the way for growing other complete replacement body parts. He says teeth are relatively safe because if a tooth fails, it can simply be extracted. http://tinyurl.com/c u7bxec Dan Soton
  • Score: 0

11:13am Tue 29 May 12

dsm says...

Another fantastic development by Southampton Orthopaedic researchers to go with the new treatment of knee osteoarthritis. Yet instead of welcoming it, the usual suspects use the news as a soapbox to peddle their tired nonsense about fluoridation.
Why do you think that the British are continually ridiculed abroad for the poor state of their dentition? Fluoridation is mandatory in US water and had been proved to reduce childhood cavities by 50-60%.
Another fantastic development by Southampton Orthopaedic researchers to go with the new treatment of knee osteoarthritis. Yet instead of welcoming it, the usual suspects use the news as a soapbox to peddle their tired nonsense about fluoridation. Why do you think that the British are continually ridiculed abroad for the poor state of their dentition? Fluoridation is mandatory in US water and had been proved to reduce childhood cavities by 50-60%. dsm
  • Score: 0

7:19pm Tue 29 May 12

Dan Soton says...

dsm wrote:
Another fantastic development by Southampton Orthopaedic researchers to go with the new treatment of knee osteoarthritis. Yet instead of welcoming it, the usual suspects use the news as a soapbox to peddle their tired nonsense about fluoridation.
Why do you think that the British are continually ridiculed abroad for the poor state of their dentition? Fluoridation is mandatory in US water and had been proved to reduce childhood cavities by 50-60%.
DSM, what have you against using stem cells to regrow teeth or parts of teeth.?
-

Princess Anne has just opened a 54m Scottish stem cell research centre that provides work for 250 stem cell scientists.

no doubt in my mind.. Mr Douglas Dunlop, Professor Richard Oreffo and all 250 scientists without question are in favor of Dental Stem Cell research.
-

see below report by The Royal Society of Edinburgh and The Caledonian Research Foundation

-

Department of Craniofacial Development, Dental Institute, King’s College, London.

Tooth morphogenesis: from embryonic development to postnatal tooth regeneration.

For thousands of years, man has replaced lost teeth.

Today we tend to use dental implants, involving a metal substitute for the root – not so very different from an iron peg found in the mouth of a Roman
from 2,000 years ago. It’s all been about inert substances, not biology, said Professor Sharpe.

All this could be about to change. He described the development of a biological process to use stem cells to create replacement teeth. This could have huge quality-of-life benefits; could revolutionise treatments for people with diseases such as osteoporosis (who may lose teeth and the bone in the jaw) and could also provide important clues for how best to use stem cells to replace other organs.

http://tinyurl.com/c
z4nf4a
[quote][p][bold]dsm[/bold] wrote: Another fantastic development by Southampton Orthopaedic researchers to go with the new treatment of knee osteoarthritis. Yet instead of welcoming it, the usual suspects use the news as a soapbox to peddle their tired nonsense about fluoridation. Why do you think that the British are continually ridiculed abroad for the poor state of their dentition? Fluoridation is mandatory in US water and had been proved to reduce childhood cavities by 50-60%.[/p][/quote]DSM, what have you against using stem cells to regrow teeth or parts of teeth.? - Princess Anne has just opened a 54m Scottish stem cell research centre that provides work for 250 stem cell scientists. no doubt in my mind.. Mr Douglas Dunlop, Professor Richard Oreffo and all 250 scientists without question are in favor of Dental Stem Cell research. - see below report by The Royal Society of Edinburgh and The Caledonian Research Foundation - Department of Craniofacial Development, Dental Institute, King’s College, London. Tooth morphogenesis: from embryonic development to postnatal tooth regeneration. For thousands of years, man has replaced lost teeth. Today we tend to use dental implants, involving a metal substitute for the root – not so very different from an iron peg found in the mouth of a Roman from 2,000 years ago. It’s all been about inert substances, not biology, said Professor Sharpe. All this could be about to change. He described the development of a biological process to use stem cells to create replacement teeth. This could have huge quality-of-life benefits; could revolutionise treatments for people with diseases such as osteoporosis (who may lose teeth and the bone in the jaw) and could also provide important clues for how best to use stem cells to replace other organs. http://tinyurl.com/c z4nf4a Dan Soton
  • Score: 0

10:04am Wed 30 May 12

dsm says...

Dan Soton

I read the article about stem cell research. However, prevention is better than cure; safer and cheaper too.
Dan Soton I read the article about stem cell research. However, prevention is better than cure; safer and cheaper too. dsm
  • Score: 0

9:23pm Fri 22 Jun 12

czlc89 says...

This is promising research, since we are hearing so much about metal hip implants. With stem cells, we can at least avoid (or reduce) the possibility of a foreign object reacting poorly with the tissues in our bodies.
http://www.newsinfer
no.com/defective-med
ical-devices/metal-o
n-metal-hip-replacem
ent-concerns-grow-in
-canada/38677
This is promising research, since we are hearing so much about metal hip implants. With stem cells, we can at least avoid (or reduce) the possibility of a foreign object reacting poorly with the tissues in our bodies. http://www.newsinfer no.com/defective-med ical-devices/metal-o n-metal-hip-replacem ent-concerns-grow-in -canada/38677 czlc89
  • Score: 0

12:35pm Sat 23 Jun 12

Dan Soton says...

Anyone interested in stem cells research ?
-

Video: Dr Dusko Ilic, King's College London, shows the BBC how stem cells for research are generated.

21 June 2012 Last updated at 11:49.
-

BBC Video: http://www.bbc.co.uk
/news/health-1849635
5
-



A warning shot on what happens when politicians (Tony Blair & Bill Clinton) and greedy scientists (Ian Wilmut ) try to control progress.. to put you in the piture scientist Ian Wilmut worked for a American company called Geron Corporation a rival to the UK's PPL.
-

February 2001.. PPL transformed Adult skin cells into beating heart cells without the use of human embryos, heralded as a Holy Grail event.
-

http://www.newscient
ist.com/dailynews/ne
ws.jsp?id=ns9999459

-

Unfortunately PPL were running out of cash and declared itself bankrupt in 2004, its stem cell research team had offres of work form all aroud the world, I believe their top scientist went to Singapore.
-

the fatal damage had been done four years earlier in February 1997 by Tony Blair & Bill Clinton, from that date on all US/UK funds for stem cell and cloning research dried up.. see below Human Cloning Debate

-

The Human Cloning Debate.

From Dolly to the Present.

In late February 1997, Ian Wilmut and his team at the Roslin Institute in Scotland announced that they had, by means of somatic cell nuclear transfer, successfully cloned the first mammal from an adult somatic cell – Dolly the sheep. President Bill Clinton and British Prime Minister Tony Blair immediately denounced any attempts to clone a human being, and the President asked his National Bioethics Advisory Commission (NBAC) to report within ninety days on the scientific, ethical, and legal questions surrounding the prospect of human cloning. Congress likewise held a series of hearings – the first one on March 12, 1997. A widespread – though not universal – consensus emerged that attempts to clone a human being would at present be irresponsible and immoral. As Wilmut explained before Congress, "Our own experiments to clone sheep from adult mammary cells required us to produce 277 'reconstructed' embryos. Of these, twenty-nine were implanted into recipient ewes, and only one developed into a live lamb. In previous work with cells from embryos, three out of five lambs died soon after birth and showed developmental abnormalities. Similar experiments with humans would be totally unacceptable." 25
-

http://biotech.law.l
su.edu/research/pbc/
reports/cloningrepor
t/historical.html

-


Tragically and possibly unrelated to all the above

-


Scientist who paved way for Dolly the sheep found hange.

The Scotsman 16 Aug 2004.

THE scientist whose pioneering research into human embryonic stem cells paved the way for the creation of Dolly the cloned sheep has been found hanged in his holiday home. The body of Professor John Clark was discovered on Thursday.
-

http://www.scotsman.
com/news/sci-tech/sc
ientist_who_paved_wa
y_for_dolly_the_shee
p_found_hanged_1_543
721
Anyone interested in stem cells research ? - Video: Dr Dusko Ilic, King's College London, shows the BBC how stem cells for research are generated. 21 June 2012 Last updated at 11:49. - BBC Video: http://www.bbc.co.uk /news/health-1849635 5 - A warning shot on what happens when politicians (Tony Blair & Bill Clinton) and greedy scientists (Ian Wilmut ) try to control progress.. to put you in the piture scientist Ian Wilmut worked for a American company called Geron Corporation a rival to the UK's PPL. - February 2001.. PPL transformed Adult skin cells into beating heart cells without the use of human embryos, heralded as a Holy Grail event. - http://www.newscient ist.com/dailynews/ne ws.jsp?id=ns9999459 - Unfortunately PPL were running out of cash and declared itself bankrupt in 2004, its stem cell research team had offres of work form all aroud the world, I believe their top scientist went to Singapore. - the fatal damage had been done four years earlier in February 1997 by Tony Blair & Bill Clinton, from that date on all US/UK funds for stem cell and cloning research dried up.. see below Human Cloning Debate - The Human Cloning Debate. From Dolly to the Present. In late February 1997, Ian Wilmut and his team at the Roslin Institute in Scotland announced that they had, by means of somatic cell nuclear transfer, successfully cloned the first mammal from an adult somatic cell – Dolly the sheep. President Bill Clinton and British Prime Minister Tony Blair immediately denounced any attempts to clone a human being, and the President asked his National Bioethics Advisory Commission (NBAC) to report within ninety days on the scientific, ethical, and legal questions surrounding the prospect of human cloning. Congress likewise held a series of hearings – the first one on March 12, 1997. A widespread – though not universal – consensus emerged that attempts to clone a human being would at present be irresponsible and immoral. As Wilmut explained before Congress, "Our own experiments to clone sheep from adult mammary cells required us to produce 277 'reconstructed' embryos. Of these, twenty-nine were implanted into recipient ewes, and only one developed into a live lamb. In previous work with cells from embryos, three out of five lambs died soon after birth and showed developmental abnormalities. Similar experiments with humans would be totally unacceptable." 25 - http://biotech.law.l su.edu/research/pbc/ reports/cloningrepor t/historical.html - Tragically and possibly unrelated to all the above - Scientist who paved way for Dolly the sheep found hange. The Scotsman 16 Aug 2004. THE scientist whose pioneering research into human embryonic stem cells paved the way for the creation of Dolly the cloned sheep has been found hanged in his holiday home. The body of Professor John Clark was discovered on Thursday. - http://www.scotsman. com/news/sci-tech/sc ientist_who_paved_wa y_for_dolly_the_shee p_found_hanged_1_543 721 Dan Soton
  • Score: 0

12:44pm Sat 23 Jun 12

Dan Soton says...

Anyone interested in stem cells research ?
-

Video: Dr Dusko Ilic, King's College London, shows the BBC how stem cells for research are generated from spare embryos donated by couples at the Assisted Conception Unit at Guy's Hospital, London.

21 June 2012 Last updated at 11:49.
-

BBC Video.. http://www.bbc.co.uk
/news/health-1849635
5
-



A warning shot on what happens when politicians (Tony Blair & Bill Clinton) and greedy scientists (Ian Wilmut ) try to control progress.. to put you in the picture scientist Ian Wilmut worked for a American company called Geron Corporation a rival to the UK's PPL.
-

February 2001.. PPL transformed Adult skin cells into beating heart cells without the use of human embryos, heralded as a Holy Grail event.
-

http://www.newscient
ist.com/dailynews/ne
ws.jsp?id=ns9999459

-

Unfortunately PPL were running out of cash and declared itself bankrupt in 2004, its stem cell research team had offers of work form all aroud the world, I believe their top scientist went to Singapore.
-

the fatal damage had been done four years earlier in February 1997 by Tony Blair & Bill Clinton, from that date on all US/UK funds for stem cell and cloning research dried up.. see below Human Cloning Debate

-

The Human Cloning Debate.

From Dolly to the Present.

In late February 1997, Ian Wilmut and his team at the Roslin Institute in Scotland announced that they had, by means of somatic cell nuclear transfer, successfully cloned the first mammal from an adult somatic cell – Dolly the sheep. President Bill Clinton and British Prime Minister Tony Blair immediately denounced any attempts to clone a human being, and the President asked his National Bioethics Advisory Commission (NBAC) to report within ninety days on the scientific, ethical, and legal questions surrounding the prospect of human cloning. Congress likewise held a series of hearings – the first one on March 12, 1997. A widespread – though not universal – consensus emerged that attempts to clone a human being would at present be irresponsible and immoral. As Wilmut explained before Congress, "Our own experiments to clone sheep from adult mammary cells required us to produce 277 'reconstructed' embryos. Of these, twenty-nine were implanted into recipient ewes, and only one developed into a live lamb. In previous work with cells from embryos, three out of five lambs died soon after birth and showed developmental abnormalities. Similar experiments with humans would be totally unacceptable."
-

http://biotech.law.l
su.edu/research/pbc/
reports/cloningrepor
t/historical.html

-


Tragically and possibly unrelated to all the above

-


Scientist who paved way for Dolly the sheep found hange.

The Scotsman 16 Aug 2004.

THE scientist whose pioneering research into human embryonic stem cells paved the way for the creation of Dolly the cloned sheep has been found hanged in his holiday home. The body of Professor John Clark was discovered on Thursday.
-

http://www.scotsman.
com/news/sci-tech/sc
ientist_who_paved_wa
y_for_dolly_the_shee
p_found_hanged_1_543
721
Anyone interested in stem cells research ? - Video: Dr Dusko Ilic, King's College London, shows the BBC how stem cells for research are generated from spare embryos donated by couples at the Assisted Conception Unit at Guy's Hospital, London. 21 June 2012 Last updated at 11:49. - BBC Video.. http://www.bbc.co.uk /news/health-1849635 5 - A warning shot on what happens when politicians (Tony Blair & Bill Clinton) and greedy scientists (Ian Wilmut ) try to control progress.. to put you in the picture scientist Ian Wilmut worked for a American company called Geron Corporation a rival to the UK's PPL. - February 2001.. PPL transformed Adult skin cells into beating heart cells without the use of human embryos, heralded as a Holy Grail event. - http://www.newscient ist.com/dailynews/ne ws.jsp?id=ns9999459 - Unfortunately PPL were running out of cash and declared itself bankrupt in 2004, its stem cell research team had offers of work form all aroud the world, I believe their top scientist went to Singapore. - the fatal damage had been done four years earlier in February 1997 by Tony Blair & Bill Clinton, from that date on all US/UK funds for stem cell and cloning research dried up.. see below Human Cloning Debate - The Human Cloning Debate. From Dolly to the Present. In late February 1997, Ian Wilmut and his team at the Roslin Institute in Scotland announced that they had, by means of somatic cell nuclear transfer, successfully cloned the first mammal from an adult somatic cell – Dolly the sheep. President Bill Clinton and British Prime Minister Tony Blair immediately denounced any attempts to clone a human being, and the President asked his National Bioethics Advisory Commission (NBAC) to report within ninety days on the scientific, ethical, and legal questions surrounding the prospect of human cloning. Congress likewise held a series of hearings – the first one on March 12, 1997. A widespread – though not universal – consensus emerged that attempts to clone a human being would at present be irresponsible and immoral. As Wilmut explained before Congress, "Our own experiments to clone sheep from adult mammary cells required us to produce 277 'reconstructed' embryos. Of these, twenty-nine were implanted into recipient ewes, and only one developed into a live lamb. In previous work with cells from embryos, three out of five lambs died soon after birth and showed developmental abnormalities. Similar experiments with humans would be totally unacceptable." - http://biotech.law.l su.edu/research/pbc/ reports/cloningrepor t/historical.html - Tragically and possibly unrelated to all the above - Scientist who paved way for Dolly the sheep found hange. The Scotsman 16 Aug 2004. THE scientist whose pioneering research into human embryonic stem cells paved the way for the creation of Dolly the cloned sheep has been found hanged in his holiday home. The body of Professor John Clark was discovered on Thursday. - http://www.scotsman. com/news/sci-tech/sc ientist_who_paved_wa y_for_dolly_the_shee p_found_hanged_1_543 721 Dan Soton
  • Score: 0

5:54pm Sat 23 Jun 12

Dan Soton says...

Dan Soton wrote:
Anyone interested in stem cells research ?
-

Video: Dr Dusko Ilic, King's College London, shows the BBC how stem cells for research are generated from spare embryos donated by couples at the Assisted Conception Unit at Guy's Hospital, London.

21 June 2012 Last updated at 11:49.
-

BBC Video.. http://www.bbc.co.uk

/news/health-1849635

5
-



A warning shot on what happens when politicians (Tony Blair & Bill Clinton) and greedy scientists (Ian Wilmut ) try to control progress.. to put you in the picture scientist Ian Wilmut worked for a American company called Geron Corporation a rival to the UK's PPL.
-

February 2001.. PPL transformed Adult skin cells into beating heart cells without the use of human embryos, heralded as a Holy Grail event.
-

http://www.newscient

ist.com/dailynews/ne

ws.jsp?id=ns9999459

-

Unfortunately PPL were running out of cash and declared itself bankrupt in 2004, its stem cell research team had offers of work form all aroud the world, I believe their top scientist went to Singapore.
-

the fatal damage had been done four years earlier in February 1997 by Tony Blair & Bill Clinton, from that date on all US/UK funds for stem cell and cloning research dried up.. see below Human Cloning Debate

-

The Human Cloning Debate.

From Dolly to the Present.

In late February 1997, Ian Wilmut and his team at the Roslin Institute in Scotland announced that they had, by means of somatic cell nuclear transfer, successfully cloned the first mammal from an adult somatic cell – Dolly the sheep. President Bill Clinton and British Prime Minister Tony Blair immediately denounced any attempts to clone a human being, and the President asked his National Bioethics Advisory Commission (NBAC) to report within ninety days on the scientific, ethical, and legal questions surrounding the prospect of human cloning. Congress likewise held a series of hearings – the first one on March 12, 1997. A widespread – though not universal – consensus emerged that attempts to clone a human being would at present be irresponsible and immoral. As Wilmut explained before Congress, "Our own experiments to clone sheep from adult mammary cells required us to produce 277 'reconstructed' embryos. Of these, twenty-nine were implanted into recipient ewes, and only one developed into a live lamb. In previous work with cells from embryos, three out of five lambs died soon after birth and showed developmental abnormalities. Similar experiments with humans would be totally unacceptable."
-

http://biotech.law.l

su.edu/research/pbc/

reports/cloningrepor

t/historical.html

-


Tragically and possibly unrelated to all the above

-


Scientist who paved way for Dolly the sheep found hange.

The Scotsman 16 Aug 2004.

THE scientist whose pioneering research into human embryonic stem cells paved the way for the creation of Dolly the cloned sheep has been found hanged in his holiday home. The body of Professor John Clark was discovered on Thursday.
-

http://www.scotsman.

com/news/sci-tech/sc

ientist_who_paved_wa

y_for_dolly_the_shee

p_found_hanged_1_543

721
Re: Tony Blair & Bill Clinton's fatal damage to PPL/Dolly cloner & UK/US Stem Cell Research.
-


Singapore Acts as Haven for Stem Cell Research.

By WAYNE ARNOLD.
Published: August 17, 2006.

Two of America’s most prominent cancer researchers, Neal G. Copeland and Nancy A. Jenkins, are planning to arrive here next month to take posts at the Institute of Molecular and Cell Biology. The husband-and-wife team, who worked for 20 years at the National Cancer Institute in Maryland, said politics and budget cuts had left financing in the United States too hard to come by.

In 2004, the British cancer expert Sir David P. Lane, renowned for his discovery of the p53 tumor-suppressing gene and for his warnings that financing shortages would lead to a British brain drain, announced that he, too, would move to Biopolis. He is now the executive director of Biopolis’s cell biology institute.

Probably the best known of Singapore’s imports was also one of its first — Alan Colman, who helped clone Dolly the sheep in 1996. Unable to find backers willing to wait for his research on diabetes to pay off, he found a ready investor in the Economic Development Board in Singapore, which helped finance ES Cell with a group of Australian investors.
-

http://www.nytimes.c
om/2006/08/17/busine
ss/worldbusiness/17s
tem.html?pagewanted=
all

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What we see at Southampton is a miner miracle given (with morals of alley cats) Tony Blair/Bill Clinton/George W. Bush had powerful unwavering animosity's directed at Stem Cell Research, no doubt about it political interference put Stem Cell Research on the back burner for 10 years, now its catch up time, I wish Southampton all the best in their future endeavors.
[quote][p][bold]Dan Soton[/bold] wrote: Anyone interested in stem cells research ? - Video: Dr Dusko Ilic, King's College London, shows the BBC how stem cells for research are generated from spare embryos donated by couples at the Assisted Conception Unit at Guy's Hospital, London. 21 June 2012 Last updated at 11:49. - BBC Video.. http://www.bbc.co.uk /news/health-1849635 5 - A warning shot on what happens when politicians (Tony Blair & Bill Clinton) and greedy scientists (Ian Wilmut ) try to control progress.. to put you in the picture scientist Ian Wilmut worked for a American company called Geron Corporation a rival to the UK's PPL. - February 2001.. PPL transformed Adult skin cells into beating heart cells without the use of human embryos, heralded as a Holy Grail event. - http://www.newscient ist.com/dailynews/ne ws.jsp?id=ns9999459 - Unfortunately PPL were running out of cash and declared itself bankrupt in 2004, its stem cell research team had offers of work form all aroud the world, I believe their top scientist went to Singapore. - the fatal damage had been done four years earlier in February 1997 by Tony Blair & Bill Clinton, from that date on all US/UK funds for stem cell and cloning research dried up.. see below Human Cloning Debate - The Human Cloning Debate. From Dolly to the Present. In late February 1997, Ian Wilmut and his team at the Roslin Institute in Scotland announced that they had, by means of somatic cell nuclear transfer, successfully cloned the first mammal from an adult somatic cell – Dolly the sheep. President Bill Clinton and British Prime Minister Tony Blair immediately denounced any attempts to clone a human being, and the President asked his National Bioethics Advisory Commission (NBAC) to report within ninety days on the scientific, ethical, and legal questions surrounding the prospect of human cloning. Congress likewise held a series of hearings – the first one on March 12, 1997. A widespread – though not universal – consensus emerged that attempts to clone a human being would at present be irresponsible and immoral. As Wilmut explained before Congress, "Our own experiments to clone sheep from adult mammary cells required us to produce 277 'reconstructed' embryos. Of these, twenty-nine were implanted into recipient ewes, and only one developed into a live lamb. In previous work with cells from embryos, three out of five lambs died soon after birth and showed developmental abnormalities. Similar experiments with humans would be totally unacceptable." - http://biotech.law.l su.edu/research/pbc/ reports/cloningrepor t/historical.html - Tragically and possibly unrelated to all the above - Scientist who paved way for Dolly the sheep found hange. The Scotsman 16 Aug 2004. THE scientist whose pioneering research into human embryonic stem cells paved the way for the creation of Dolly the cloned sheep has been found hanged in his holiday home. The body of Professor John Clark was discovered on Thursday. - http://www.scotsman. com/news/sci-tech/sc ientist_who_paved_wa y_for_dolly_the_shee p_found_hanged_1_543 721[/p][/quote]Re: Tony Blair & Bill Clinton's fatal damage to PPL/Dolly cloner & UK/US Stem Cell Research. - Singapore Acts as Haven for Stem Cell Research. By WAYNE ARNOLD. Published: August 17, 2006. Two of America’s most prominent cancer researchers, Neal G. Copeland and Nancy A. Jenkins, are planning to arrive here next month to take posts at the Institute of Molecular and Cell Biology. The husband-and-wife team, who worked for 20 years at the National Cancer Institute in Maryland, said politics and budget cuts had left financing in the United States too hard to come by. In 2004, the British cancer expert Sir David P. Lane, renowned for his discovery of the p53 tumor-suppressing gene and for his warnings that financing shortages would lead to a British brain drain, announced that he, too, would move to Biopolis. He is now the executive director of Biopolis’s cell biology institute. Probably the best known of Singapore’s imports was also one of its first — Alan Colman, who helped clone Dolly the sheep in 1996. Unable to find backers willing to wait for his research on diabetes to pay off, he found a ready investor in the Economic Development Board in Singapore, which helped finance ES Cell with a group of Australian investors. - http://www.nytimes.c om/2006/08/17/busine ss/worldbusiness/17s tem.html?pagewanted= all - What we see at Southampton is a miner miracle given (with morals of alley cats) Tony Blair/Bill Clinton/George W. Bush had powerful unwavering animosity's directed at Stem Cell Research, no doubt about it political interference put Stem Cell Research on the back burner for 10 years, now its catch up time, I wish Southampton all the best in their future endeavors. Dan Soton
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7:16am Tue 26 Jun 12

Dan Soton says...

Re: Funds For Dental Stem Cell Research Vs The Fluoridation of Southampton's drinking water.

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According to Paul Sharpe, Ph., the UKs leading Dental Stem Scientist and US dental-health surveys..
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After 60 years of community water fluoridation about 70 % of adults in the United States have lost at least one tooth; about 58 % of those aged 50 and older have fewer than the 21 teeth considered ‘functional dentition’; and about 18 % aged 65 or older have no natural teeth at all.


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Regrowing Teeth with Dental Stem Cells: An Alternative to Dentures, Bridges, and Implants.?

April 27, 2011 in New York.

The future for regenerative and tissue-engineering application to dentistry is one with immense potential, capable of bringing quantum advances in treatment for our patients.

Behind the therapeutic promise of the stem cells found in teeth is the work of scientists such as Paul Sharpe, Ph.D., a pioneer in research that promises to expand regenerative dentistry.

“In the future we envision,” explains Dr. Sharpe, “a patient who loses a tooth and wants a replacement will be able to choose between current methods and a biological-based implant—a new natural tooth—derived from the patient’s own dental stem cells.”
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http://www.prweb.com
/releases/2011/04/pr
web5258064.htm

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Questions for all Stem Scientists


With the greatest possible respect... we are told about 70–90% of ingested fluoride is absorbed into the blood, where it distributes throughout the body.. will the Fluoridation of Southampton's drinking water adversely affect/hinder Stem Cell treatment's?

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Do you support the Fluoridation of Southampton's drinking water?
Re: Funds For Dental Stem Cell Research Vs The Fluoridation of Southampton's drinking water. - According to Paul Sharpe, Ph., the UKs leading Dental Stem Scientist and US dental-health surveys.. - After 60 years of community water fluoridation about 70 % of adults in the United States have lost at least one tooth; about 58 % of those aged 50 and older have fewer than the 21 teeth considered ‘functional dentition’; and about 18 % aged 65 or older have no natural teeth at all. --------- Regrowing Teeth with Dental Stem Cells: An Alternative to Dentures, Bridges, and Implants.? April 27, 2011 in New York. The future for regenerative and tissue-engineering application to dentistry is one with immense potential, capable of bringing quantum advances in treatment for our patients. Behind the therapeutic promise of the stem cells found in teeth is the work of scientists such as Paul Sharpe, Ph.D., a pioneer in research that promises to expand regenerative dentistry. “In the future we envision,” explains Dr. Sharpe, “a patient who loses a tooth and wants a replacement will be able to choose between current methods and a biological-based implant—a new natural tooth—derived from the patient’s own dental stem cells.” - http://www.prweb.com /releases/2011/04/pr web5258064.htm - Questions for all Stem Scientists With the greatest possible respect... we are told about 70–90% of ingested fluoride is absorbed into the blood, where it distributes throughout the body.. will the Fluoridation of Southampton's drinking water adversely affect/hinder Stem Cell treatment's? - Do you support the Fluoridation of Southampton's drinking water? Dan Soton
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