Leicester begin life after Claudio Ranieri with a home clash against Liverpool on Monday, while leaders Chelsea host Swansea.
The second leg will come just two days after United’s FA Cup quarter-final, but will be played at Old Trafford.
From the highs of the title to the lows of the relegation zone, we look at the Foxes under Ranieri.
The club paid tribute to their manager’s achievements but said their perilous league position required action.
Mourinho v Puel. It’s a contrast that could hardly be starker. It’s the extrovert against the introvert. The high profile v the understated. The controversial taking on the analytical.
Conte laughed off suggestions his job would be at risk if Chelsea become Premier League champions.
The Italian wants Watford to turn Vicarage Road into a fortress as they look to steer clear of a relegation battle.
Chairman Sir Chips Keswick was positive about the “robust” figures.
Hull boss unaware of Uruguayan striker’s potential switch to the Chinese Super League.
Could Nigel Pearson make a return to the King Power Stadium?