Roy Hodgson's side earned many plaudits for the manner in which they excited and enthralled against Italy, yet Saturday's match ended in a frustrating 2-1 loss.
Defeat to the four-time champions is no disgrace but leaves England needing a positive result against Uruguay in Sao Paulo on Thursday.
Oscar Tabarez's side are in the same boat after suffering an embarrassing 3-1 loss to Costa Rica, meaning defeat would all-but end either sides' hopes of making it out of Group D.
''It's massive for us,'' said Saints captain Lallana. ''We have to go all-out, but we know we need the win and we're confident.
''There were signs the other night that we're close and the lads know that it's all or nothing really.
''We've got great confidence in the camp and I'm certainly confident that we're going to get the win.
''We knew from the start that we'd be in a tough group and the Uruguayans are a tough team, but we're a strong team and we've got a great group of players.
''With just a few tweaks we can get this result.''